Oxidative phosphorylation (OXPHOS) is a fundamental process for cellular energy production, responsible for ATP synthesis via the mitochondrial electron transport chain. Disruptions in OXPHOS function have been linked to metabolic disorders, neurodegenerative diseases, and cancer, making it a critical area of research in cell biology and disease modeling.
The OXPHOS Cocktail from Proteintech is a highly sensitive, validated antibody mix designed for the simultaneous detection of all five OXPHOS complexes (Complex I-V) in human samples. Optimized for Western blotting, this cocktail provides clear, reproducible, and publication-quality data, making it an essential tool for mitochondrial research.
OXPHOS Cocktail – Your go-to antibody kit for mitochondrial research
This premium antibody cocktail enables efficient detection of the relative expression levels of all five mitochondrial OXPHOS complexes in a single assay. Whether studying mitochondrial dysfunction, bioenergetics, or disease progression, the OXPHOS Cocktail provides a streamlined and cost-effective solution.
Key benefits of the OXPHOS cocktail:
- Complete target coverage – Detects all five mitochondrial OXPHOS complexes (Complex I-V).
- Western blot optimized – Provides robust, high-sensitivity detection.
- Exceptional signal quality – Clear band resolution with minimal background.
- Human-specific reactivity – Designed for relevance in biomedical research.
- Cost-effective – High-quality antibody mix at a competitive price.
Target coverage in the OXPHOS cocktail
| Target | Complex | Molecular Weight | Catalog Number |
|---|---|---|---|
| NDUFB8 | Complex I | 19-22 kDa | 14794-1-AP |
| SDHB | Complex II | 32 kDa | 10620-1-AP |
| UQCRC1 | Complex III | 45 kDa | 21705-1-AP |
| MTCO2 | Complex IV | 23-25 kDa | 55070-1-AP |
| ATP5A1 | Complex V | 50-55 kDa | 14676-1-AP |
Western blot – High-quality data for your research
The OXPHOS Cocktail is specifically validated for Western blot applications, delivering exceptional sensitivity and clear, high-resolution results.
- Tested on multiple cell lines – Proven performance in HeLa, HepG2, and other human lysates.
- Optimized for strong signal clarity – 1:4,000 dilution ensures high signal strength with minimal background.
- Cost-effective solution – Available at an introductory price of €287 for 100 µL.
Western blot validation:
- Various lysates were separated by SDS-PAGE and incubated with the OXPHOS Cocktail (1:4,000 dilution).
- The five mitochondrial OXPHOS complexes were detected clearly and consistently.
Learn more & purchase from our supplier
The OXPHOS Cocktail is available exclusively through Proteintech, a trusted provider of high-quality antibodies for mitochondrial research. Visit their website to explore detailed product specifications, validation data, and ordering options.
