We simplify the process of RNA clean-up with our broad portfolio of kits from Zymo Research. Explore the best RNA clean-up and concentration kits for desired formats and targets. The kits are reliable and can effectively purify RNA samples for sensitive downstream applications such as microarrays, RNA transfection, denaturing-gel electrophoresis, Northern blotting, RT-(q)PCR, and Next-Gen Sequencing. Obtain concentrated, inhibitor-free RNA from a wide variety of preparations.

Our products for RNA clean-up and concentration

Overview table RNA clean-up and concentration kits

 RNA Clean & Concentrator™ (RCC)Oligo Clean & Concentrator™ (OCC)OneStep™ PCR Inhibitor Removal KitsZymoclean™ Gel RNA Recovery Kit ZR Small-RNA™ PAGE Recovery Kit
Nucleic acid

dsDNA
cDNA
dsRNA
ssRNA

dsDNA
cDNA
dsRNA
ssRNA

dsDNA
cDNA
dsRNA
ssRNA

dsDNA
cDNA
dsRNA
ssRNA

dsDNA
cDNA
dsRNA
ssRNA

Fragment size≥ 17 nt16 - 200 ntOnly binds inhibitors≥ 500 nt≥ 17 nt
Format
  • Column
  • 96-well
  • Magnetic bead
  • Column
  • 96-well
  • Column
  • 96-well
  • Column
  • Column
Common applicationsExtracted or transcribed RNA clean-upSmall oligo clean-upEnvironmental inhibitor removalRNA size selection from agarose gelsSmall RNA size selection from PAGE gels
RemovesSalts, protein, unincorporated dyes/fluorescence and nucleotides, and phenolHumic acids, tannins, polyphenolics, melaninSalts, proteins, and unwanted fragments based on size

Learn more about selecting the right nucleic acid clean-up kit in our blog.         Go to blog

RNA Clean & Concentrator™ Kits – Extracted/transcribed RNA clean-up

RNA Clean & Concentrator kits offer a fast and dependable solution for preparing high-quality RNA. Utilizing a unique single-buffer system and Zymo-Spin™ technology, these kits simplify the process of RNA clean-up: just add the binding buffer to your sample, adjust binding conditions by adding ethanol, wash, and elute the RNA. These kits safely process RNA fragments with a length of ≥ 17 bases. Recover >90% and elute in as little as 6 μl to obtain highly concentrated RNA perfectly suited for various downstream applications.

Comparison table RNA Clean & Concentrator Kits

ProductSpecificationsUses
RNA Clean & Concentrator™-5Format: Spin-Column
Elution volume: ≥ 6 μl
Binding capacity: 10 μg
RNA size limits: ≥ 17 nt
Processing time: 5 min

RNA clean-up
DNA-free RNA
Enzyme removal
Nucleotide/dye removal
Small-RNA/probe purification

RNA Clean & Concentrator™-5 w/ DNase I

RNA Clean & Concentrator™-96

Format: 96-Well Plate
Elution volume: ≥ 10 μl
Binding capacity: 10 μg
RNA size limits: ≥ 17 nt
Processing time: 20 min

RNA Clean & Concentrator™-25

Format: Spin-Columns
Elution volume: ≥ 25 μl
Binding capacity: 50 μg
RNA size limits: ≥ 17 nt
Processing Time: 5 min
RNA Clean & Concentrator™-100Format: Spin-Columns
Elution volume: ≥ 100 μl
Binding capacity: 1 mg
RNA size limits: ≥ 17 nt
Processing time: 15 min
RNA Clean & Concentrator™ MagBead KitFormat: Magnetic Bead
Elution volume: ≥ 15 μl
Binding capacity: 10 μg
RNA size limits: ≥ 17 nt
RNA clean-up
Automation
RNA Clean & Concentrator™ MagBead Kit (supplied with DNase I Set)
Cat-No.ItemSizePrice (CHF)
R1015RNA Clean & Concentrator-5 w/ Zymo-Spin IC Columns (Capped)50 preparations205.00
R1016RNA RNA Clean & Concentrator-5 w/ Zymo-Spin IC Columns (Capped)200 preparations698.00
R1013RNA Clean & Concentrator-5 with DNase I Set50 preparations245.00
R1014RNA Clean & Concentrator-5 with DNase I Set200 preparations841.00
R1080ZR-96 RNA Clean & Concentrator Kit2 x 96 preparations620.00
R1017RNA Clean & Concentrator-25 w/ Zymo-Spin IIC Columns (Capped)50 preparations205.00
R1018RNA Clean & Concentrator-25 w/ Zymo-Spin IIC Columns (Capped)100 preparations366.00
R1019RNA Clean & Concentrator-100 w/ Zymo-Spin V-E Columns w/ Reservoir (Capped)25 preparations272.00
R1081RNA Clean & Concentrator MagBead96 preparations321.00
R1082RNA Clean & Concentrator MagBead (supplied with DNaseI set)96 preparations390.00

Oligo Clean & Concentrator™ Kits – Small oligo clean-up

The Oligo Clean & Concentrator simplifies the recovery and clean-up of DNA/RNA fragments and oligonucleotides ≥ 16 nt from labeling (radioactive, biotin, DIG, etc.) and enzymatic reactions. The clean-up procedure effectively removes contaminants, including unincorporated nucleotides, short oligos, dyes, enzymes, and salts, concentrating DNA/RNA into a small volume of water. Purified DNA/RNA is ready in just 2 minutes and can be used for hybridization, gel shift assays, enzymatic reactions, ligation, sequencing, microarray analysis, and more.

Cat-No.ItemSizePrice (CHF)
D4060Oligo Clean & Concentrator50 preparations124.00
D4061Oligo Clean & Concentrator200 preparations468.00
D4062ZR-96 Oligo Clean & Concentrator2 x 96 well plate310.00
D4063ZR-96 Oligo Clean & Concentrator4 x 96 well plate609.00

OneStep™ PCR Inhibitor Removal Kits – Environmental inhibitor removal

Cat-No.ItemSizePrice (CHF)
D6031OneStep PCR Inhibitor Removal Kit50 preparations164.00
D6035OneStep-96 PCR Inhibitor Removal Kit2 x 96 preparations505.00

Designed for efficient contaminant removal, the OneStep PCR Inhibitor Removal Kits include everything required to remove substances that potentially inhibit downstream enzymatic processes (such as PCR and reverse transcription) from DNA and RNA samples. The column and plate formats are specifically designed to effectively eliminate polyphenolic compounds, humic and fulvic acids, tannins, melanin, and similar impurities from even the most impure preparations. The cleanup process is straightforward – apply the sample, spin, and recover. The kits ensure recovery of ≥ 80% DNA and RNA, free from PCR inhibitors.

Zymoclean™ Gel RNA Recovery Kit – RNA size selection from agarose gels

Recover purified RNA fragments from agarose gels in just 30 minutes using the Zymoclean Gel RNA Recovery Kit. This kit combines a unique single-step agarose dissolving/RNA binding buffer with Zymo-Spin™ Column technology to obtain high-quality RNA. The RNA is eluted in small volumes of DNase/RNase-Free Water, resulting in highly concentrated samples for subsequent RNA-based workflows. Compatible with MOPS, TAE, and TBE buffered agarose gels (formaldehyde up to 2.0%), the kit achieves ≥ 80% recovery for RNA > 500 nt.

Cat-No.ItemSizePrice (CHF)
R1011Zymoclean Gel RNA Recovery Kit w/ Zymo-Spin IC Columns (Capped)50 preparations185.00

ZR small-RNA™ PAGE Recovery Kit – Small RNA size selection from PAGE gels

Extract high-quality small RNAs from native or denatured polyacrylamide gels using the ZR small-RNA PAGE Recovery Kit. This advanced kit enhances the "crush and soak" method with a unique buffer system and Zymo-Spin™ Column technologies, ensuring superior recovery and convenience. Recovered RNA can be concentrated to ≥ 6 μl, making it suitable for downstream enzymatic reactions and manipulations. The kit is compatible with gels up to 25% (w/v) polyacrylamide and can also be used for extraction/isolation of DNA fragments with equal efficiency.

Cat-No.ItemSizePrice (CHF)
R1070ZR small-RNA PAGE Recovery Kit20 preparations206.00

ssDNA/RNA Clean & Concentrator™ – Single-stranded nucleic acid clean-up

Cat-No.ItemSizePrice (CHF)
D7010ssDNA/RNA Clean & Concentrator Kit20 preparations128.00
D7011ssDNA/RNA Clean & Concentrator50 preparations258.00

The ssDNA/RNA Clean & Concentrator offers a fast and reliable solution for the separation of up to 10 µg of single-stranded DNA and/or RNA (e.g., short transcripts, probes, primers) from double-stranded species like genomic DNA. The procedure takes only 10 minutes and employs a single-buffer system with Zymo-Spin™ column technology. The kit enables safe recovery of ssDNA/RNA ranging from 17 to 200 nucleotides, resulting in highly purified, concentrated samples for use in molecular techniques.

Free samples

Curious? We offer free samples for many products from Zymo Research. Try them now!*

Download list of free samples       Request free samples here

In order to request a sample, you must be affiliated with a Swiss research lab (academic or commercial). We do not ship samples to customers outside Switzerland. By placing an order, you agree to test the sample and provide feedback within 3 weeks of sample receipt.

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Zymo Research

Zymo Research is a leader in molecular biology, offering a comprehensive range of products for DNA, RNA, and epigenetics research. Established in California in 1994, the company is renowned for its high-quality nucleic acid purification technologies, including kits and reagents for DNA and RNA clean-up, isolation, and sequencing. Zymo is also a pioneer in epigenetics, with products for DNA methylation analysis, chromatin analysis, and NGS library preparation. Each product is designed to be simple to use, reliable, and available at competitive prices, making them ideal for both academic and biopharmaceutical research.

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Norgen Biotek

Norgen Biotek are experts in sample collection and preparation. In addition to the topselling RNA Purification Kit line, Norgen also offers tools for the collection and analysis of microbiome samples. 

About Norgen Biotek                 Shop for Norgen Biotek products