News

LubioScience partners with Zymo Research for next-generation sequencing

LubioScience GmbH, Switzerland’s leading life science distributor, has partnered with Zymo Research to bring specialized Next-Generation Sequencing (NGS) services for epigenetics and microbiomics to the Swiss market. This collaboration enables Swiss biotech companies to obtain reliable NGS data with faster turnaround times and highly competitive pricing.

LubioScience and IDT launch gene product for biotech applications

LubioScience, Switzerland’s largest R&D reagent platform, has teamed up with Integrated DNA Technologies (IDT) to launch Rapid Genes, a revolutionary product designed to streamline high-throughput workflows. The genes are shipped in as little as five business days, offering speed and precision that will significantly benefit researchers and biotech companies.

LubioScience Expands Product Portfolio with Fresh Human Blood Products and Biospecimens for Enhanced Research Opportunities

LubioScience GmbH, Switzerland’s leading Life Sciences platform, is pleased to announce the expansion of its product portfolio with the addition of fresh human blood products and biospecimens provided by Research Donors from the UK. This enhancement enables researchers to access precisely defined blood samples to support their research and development activities.

New year, new look for LubioScience!

We are excited to announce that LubioScience got a new look following the addition to Europa Biosite!

LubioScience is now part of Europa Biosite

We are proud to announce that LubioScience is now part of Europa Biosite.

2023 Lubio BBQ in Schlieren

Fancy a sausage hot off the grill? Or a slice of spicy Halumi?

Then join us for our annual BBQ event in Schlieren!

LubioSciences and IDT launch new longer e-Blocks Gene Fragments for Antibody Discovery

We are proud to announce the establishment of a new custom services portfolio.

LubioScience launches Next Generation Sequencing services in Switzerland

We are proud to announce the establishment of a new custom services portfolio.

LubioScience launches antibody sequencing and production services in Switzerland

We are proud to announce the establishment of a new custom services portfolio.

LubioScience announces new Custom Services Offering

We are proud to announce the establishment of a new custom services portfolio.

New supplier: Alomone Labs

We are excited to welcome Alomone Labs to our family of trusted high quality suppliers. Alomone Labs is a leading developer, producer and supplier of reliable research tools for membrane proteins. By leveraging 30 years of experience and scientific excellence, Alomone Labs produces tried, tested and trusted research reagents.

New supplier: Reagecon

LubioScience and Reagecon, the world's number one manufacturer for chemical and biological standards, have signed a distribution agreement for Switzerland.

New supplier: Krishgen Biosciences

LubioScience and Krishgen Biosciences, a manufacturer of assay & ELISA kits based in India, have signed a distribution agreement for Switzerland.

New supplier: Spirochrome

LubioScience and Spirochrome have signed an exclusive distribution agreement for Switzerland. Under the agreement, LubioScience will distribute the entire range of innovative live imaging reagents manufactured by Spirochrome.

New supplier: Huabio

Our new supplier Huabio makes exceptional recombinant antibodies and nanobodies. Every product in their catalog is made and tested in-house, backed with their HUABIO guarantee.

LubioScience is on the Distributor Spotlight over at Atlas Antibodies

LubioScience is proud to be be presented on Atlas Antibodies' blog in their special distributor spotlight segment. Head over there to find out more!

IDT Webinar: Accelerate Your Protein Engineering Workflows with gBlocks

Discover ways to overcome the time-consuming bottlenecks often found in traditional protein engineering workflows. Our speaker, Dr. Evelyn Eggenstein, the division manager of synthetic biology for Daicel Arbor Biosciences, will discuss how their high-yield myTXTL® Cell-Free Protein Expression platform, when coupled with IDT’s gBlocks™ Gene Fragments, can condense protein engineering workflows to a single day.

NGS library prep kits from Swift Biosciences: Single strand or double strand DNA/RNA input, we got it covered!

During the presentation, latest developments of library preparation methods will be covered. Starting with cfDNA or FFPE samples, degraded RNA or DNA, limited amounts, expand your capabilities, run those difficult samples. Efficient libraries from single stranded RNA or DNA using Adaptase® technology workflows and new library normalisation product called Normalase® will be discussed.

New supplier: Selenozyme

We are proud to welcome Selenozyme as a new supplier.

New supplier: ChemFaces

We welcome ChemFaces, manufacturer of natural compounds, to our portfolio.

New supplier: Indigo Biosciences

LubioScience is proud to welcome Indigo Bioscience as a new supplier.

New supplier: German Research Products

LubioScience is proud to welcome German Research Products (GRP) as its latest supplier.

Targeting glycosylated PD-L1 to enhance patients’ anti-cancer immune response

Join us and GeneTex for this webinar on the role of PD-L1 in cancer therapy! PD-L1 is a transmembrane protein involved in the suppression of the immune response.

Webinar: Whole genome & exome sequencing from low input samples using Swift Biosciences’ 2S Technology

Swift's 2S Technology yields high complexity NGS libraries and improves sample coverage, thereby revealing even difficult to read sequences in your NGS samples. Attend our webinar and learn how to harness the 2S Technology for improving coverage in your NGS experiments.

Pancreatic cancer - an insidious and stubborn foe

Join us for this webinar by A. R. Ball, Jr., M.D. on pancreatic cancer. He will talk about the anatomy, clinical features, therapeutic options and future direction of pancreatic cancer research.

Webinar series: NGS kits by Swift Biosciences

Coming up: Swift's Normalase Kit: a revolutionary library normalization technology for NGS applications.

Why you should give a HEK

Webinar: Proteintech will present the benefits to manufacturing GMP-grade proteins using HEK293 cells.

Proteintech webinar series

Returning to the lab? Blow away the cobwebs with Proteintech's antibody application refresher webinars.

Webinar series: Getting started with CRISPR/Cas9

Attend our webinar series on CRISPR/Cas9 and learn from the experts: how to properly plan a CRISPR genome editing experiment - designing your guide RNAs, getting the complex into cells, how to improve editing under challenging conditions, how to optimize HDR, troubleshooting. Don't miss this opportunity to get the best tips & tricks on how to optimize your genome editing experiments!

Swift SARS-CoV-2 Amplicon Panel: NGS in a SNAP

This webinar presents a targeted NGS strategy featuring the new Swift Normalase™ Amplicon Panel (SNAP) workflow using a SARS-CoV-2 specific panel.

The Human Protein Atlas program and SARS-CoV-2 related proteins

Webinar on integration of transcriptomics and antibody-based proteomics for cell type-specific localization of SARS-CoV-2 related proteins

Webinar: SARS-CoV-2/COVID-19: A World Problem Needing a World Response

Join GeneTex’s senior scientist Alexander Ball, M.D. for a discussion of the scientific and clinical aspects of SARS-CoV-2/COVID-19 along with an introduction to GeneTex’s SARS-CoV-2 and coronavirus catalog of reagents.

Webinar: 2S Turbo Library kit for WGS and Metagenomics

Join our webinar to learn about the Swift 2S Turbo DNA Library Kit - a quick and cost effective solution for your WGS and Metagenome applications.

Webinar: Vaccine Development for COVID-19

COVID-19 has become a major global health threat, approaching 2 million cases globally, and now extending into developing nations of Africa, Asia, and Latin America. A panel of experts from Academia and Industry discusses different approaches and current projects on the way to developing a vaccine against COVID-19.

Improving HDR rates in your CRISPR experiments - introducing the HDR donor oligos and design tool

Join our online webinar to learn how to improve HDR rates in your CRISPR experiments!

Seminars: CRISPR enzyme optimization in Basel, Lausanne & Zurich

March 10th/11th/12th: IDT Seminars on optimizing CRISPR ribonucleoproteins to achieve potent, precise genome editing

Visit our booth at the annual LS2 meeting

LubioScience will exhibit at the upcoming LS2 meeting from Feb 13 to 14, 2020 at the University of Zurich Irchel.

Visit our booth at the Lausanne Genomics Days

LubioScience will exhibit at the upcoming Lausanne Genomics Days from Feb 10 to 11, 2020 at the Génopode building of the University of Lausanne.

A New Way to Detect More Cancers Earlier

In a recent TEDx Talk, Dr. Anne Marie Lennon presented exciting clinical findings from testing a new molecular diagnostic platform developed by herself and colleagues at Johns Hopkins University. This cutting edge technology, called CancerSEEK, has the potential of being a game-changer for catching cancer earlier, by accurately detecting trace amounts of cancer DNA with a simple blood test.

Give me that CO2 - I'm hungry

Even with growing awareness of climate change, global greenhouse gas emissions are still climbing. In recent years, scientists have worked to apply advances in synthetic biology toward some of our most pressing environmental challenges, such as how to reduce global CO2 levels.

IDT webinar: How to design your qPCR and dPCR assays for optimal results

Richelle Spanjers, IDT Field Application Manager, provides guidelines for using design parameters such as Tm, GC content, amplicon size, and primer and probe location. She describes several free, online tools that can aid in primer/probe design. Additionally, a novel SNP genotyping technology will be described. rhAmp SNP increases the specificity of your assay and improves on existing 5’ nuclease genotyping assay technologies.

Free IDT webinar on custom adapters for NGS

Learn about adapters, techniques & applications on Thursday, November 28, 2019 from 3:00 PM to 4:00 PM CET

All that plastic in the lab - our tips to reduce your environmental footprint

The 3 Rs strategy — reduce, reuse and recycle — can be applied everywhere, so why not in laboratories as well? Admittedly, it is a challenge in this environment, but it is not impossible. In addition to the original three Rs, we present R numbers 4 and 5: Rethink & Replace and look forward to read your suggestions!

The living dead may buzz among us

Remember the zombie ants from one of our earlier newsletters? These unfortunate creatures fall victim to a vicious fungus and... well, you can read the gruesome story in full by following the link at the end of this blog. But as it turns out, the ants are not alone - yet another fungus is targeting our common house fly, turning it into a buzzing aerial zombie.

Broad researchers describe new CRISPR-based method called Prime Editing

The goup of David Liu at the Broad Institute has published a paper in Nature describing a novel approach to edit genomes. The method, called "prime editing" relies on a fusion between a catalytically impaired Cas9 enzyme and a reverse transcriptase. Prime editing directly writes genetic information into the genome using just a single guide RNA. No double strand breaks or exogenous DNA templates are needed for the modification.

CRISPR enters first human clinical trials

Since its debut, CRISPR gene editing has held the promise of curing genetic diseases. Now - seven years after the first CRISPR publication - the first clinical trials using the gene scissors are starting.

Clinical trials now beginning include the use of CRISPR/Cas9 to combat cancer and blood disorders. The strategy is to remove some of a person’s cells, edit the DNA and then inject the cells back in, now hopefully armed to fight disease. Researchers are also designing clinical trials to treat people with an inherited blindness. Those trials, if successful, could spur future trials for Duchenne muscular dystrophy, cystic fibrosis and a wide variety of other genetic diseases, affecting millions of people worldwide.

Improve assays with customizable oligos and probes containing cost-effective locked nucleic acids

Affinity Plus DNA & RNA Oligonucleotides and Affinity Plus qPCR Probes contain locked nucleic acid bases and are ideal for scientists with applications that require increased hybridization specificity or improved stability in their oligo designs. The locked nucleic acid bases included in these sequences increase hybrid melting temperature (Tm), and thus, hybridization specificity, improve sequence stability and nuclease resistance in vitro and in vivo, enhance SNP and mismatch discrimination and allow for design of shorter, more effectively quenched probes.

Next-Gen ChIP-Seq: Genome-Wide Single-Cell Analysis with Antibody-Guided Chromatin Tagmentation Methods

Find out how antibody-guided chromatin methods may be the future of ChIP

Meet us at the ILMAC 2019!

Come and meet us at the ILMAC in Basel this September 24th to 27th! Goodies, samples, prizes & our wheel of fortune await you!

Webinar announcement: Introducing Swift Biosciences RNA library kits for NGS

Thursday Sept 26, 2019 at 3PM CEST.

CRISPR DNA base editors cause tens of thousands of off-target RNA mutations

A team of Chinese researchers has found that CRISPR-based DNA base editors can induce tens of thousands of off-target mutations in RNA. Adenine base editors (ABEs) and cytosine base editors (CBEs) are known to efficiently and precisely edit point mutations in DNA with minimal off-target DNA editing. However, recent studies have also shown that despite their reputations for generating low levels of off-target DNA edits, base editors may create unexpected problems.

Plastics, pollution and a new bacterial hope for recycling

There have been growing concerns over the amount of waste plastic that is being released into the environment, especially into our oceans, causing enormous harm to aquatic life and contaminating our food chain. For instance, tiny plastic particles, known as microplastics, are ingested by sea life and by this route enter the human food chain.

2019 Lubio BBQ in Schlieren

Fancy a sausage hot off the grill? Or a slice of spicy Halumi?

Then join us for our annual BBQ event in Schlieren!

ETH Zurich researchers use Cas12a to develop multiplex genome engineering platform

Researchers from ETH Zurich and the University of Groningen have used CRISPR-Cas12a to develop a genome engineering platform to investigate the biology of complex cell behaviors.

The return of the zombie ants: the bite

How do we begin to comprehend the astonishing complexity of a fungus that invades an ant’s body, grows throughout its tissues, and orders the host to climb up a tree and bite onto a twig, killing it and exploding out the back of its head to rain down spores on more ants below?

CRISPR - which works better, sgRNAs or two-part cr/tracr RNAs?

In CRISPR experiments, both 2-part and single guide RNA formats provide high editing levels. For a subset of target sites, however, using a specific guide RNA format can result in better gene editing efficiencies. Review our guide RNA recommendations and performance data before setting up your next gene editing experiment.

A gut feeling - athletes' performance and the microbiome

Wish you could run the Boston Marathon in under 3 hours? The path to a successful marathon performance is usually a painful one and requires both time and the willingness to suffer on an extraordinary scale. But there may be an alternative on the horizon - stay on your couch and train your microbiome instead.

IDT Webinar: Unmatched flexibility with Lotus prep and a wealth of adapters to choose from

Learn all about the Lotus DNA Library Prep solution & how it fits in with WGS, targeted seq & more. Also get to know IDT's extensive choice of adapters.

A novel approach for targeted genomic insertion of DNA fragments

Researchers from the National Institutes of Health and the Broad Institute report a novel system for precisely inserting DNA into a genome that uses a combination of a CRISPR-associated transposase (CAST) and a CRISPR effector protein (Cas12k) from the cyanobacterium Scytonema hofmanni.

Their system, termed "ShCAST" catalyzes RNA-guided DNA transposition by unidirectionally inserting segments of DNA 60 to 66 bp downstream of the protospacer site with high efficiency. Inserting DNA fragments into the E. coli genome via ShCAST yielded insertion efficiencies of up to 80 percent, without the need for positive selection.

Webinar: Precise genome editing with A.s. Cas12a (Cpf1) Ultra: a mutant protein with the reliability of S.p. Cas9

Learn all about the CRISPR-Cas12a (Cpf1) enzyme and its improved performance, higher efficiency, and increased target range.

IDT webinar: Design considerations for qPCR & ddPCR

Quantitative PCR is one of the most commonly used techniques in molecular life sciences. However, knowing how to achieve the best results is not always straight-forward. Richelle Spanjers (Field Application Manager) provides guidelines in this webinar.

The worst disease ever recorded

Measles? The flu pandemic a century ago? Think again - the worst killer of species on our planet is actually a fungus. Bd - Batrachochytrium dendrobatidis in full - kills amphibians by eating away at their skin and triggering fatal heart attacks. Bd is suspected of having caused the decline or extinction of roughly 200 amphibian species, and that figure is most certainly out of date.

FAAH-OUT: Meet the woman who feels no pain and could open door for new generation of medicines

For decades Jo Cameron has been cheerfully bumping, burning and bruising herself in all manner of mishap, yet she never stopped to ask why her injuries did not hurt.

She gave birth to both her children without once resorting to drugs; she laughs off offers of anaesthetic during dental work, and when she burns herself while cooking, often the first she knows about it is the smell of her own burning flesh.

Nano-Secondaries: ChromoTek’s New Alpaca Secondary Antibodies

High specificity, high affinity and better resolution. ChromoTek’s new Nano-Secondaries are recombinant secondary antibodies based on the alpaca Nanobody or VHH — a small stand-alone antigen-binding entity derived from camelid heavy-chain only IgGs. These Nano-Secondaries are fully validated for their applications in immunofluorescence, super-resolution microscopy and western blot.

Subscribe to our new NGS newsletter!

Are you working with NGS or do you want to keep track of the latest developments in the field? Then subscribe to our newly launched NGS newsletter.

Molecular Dimensions presents their newest protein stability screen: the Durham Osmolyte Screen

Easily identify which of over 50 osmolyte cell components help stabilize your protein thanks to the Durham Osmolyte Screen, offered exclusively as MD1-120 with 96 x 0.5 ml conditions from Molecular Dimensions.

Researchers identify a distinct new CRISPR editing platform

In a recent study published in Nature, researchers report that they have characterized a novel set of genome editing enzymes which are fundamentally distinct from the established Cas9 and Cas12a platforms. They have named the new RNA-guided genome-editing platform CRISPR-CasX.

Lunch seminar at the CMU: CRISPR editing using chemically-modified crRNA:tracrRNA complexes

CRISPR/Cas is a simple and efficient method of gene editing that utilizes the Cas9 protein and RNA molecules as guides to either disrupt host genes or insert sequences of interest. The prospect of efficiently creating tailored changes to a gene of interest is revolutionizing biomedical research.

LubioScience becomes exclusive distributor for Calibre Scientific brands

LubioScience is proud to announce a partnership with the Calibre Scientific group for distribution in Switzerland. Lubio will become the official channel for several Calibre brands, including Anatrace, Molecular Dimensions, ProteinArk and EdgeBio. Lubio customers will profit from faster delivery times, local stock and support.

Mystery of ‘headhunting’ ants solved

The Formica archboldi ant decorates its nests with the severed heads of the bigger, nastier prey it kills - now we know how.

Cloning strategies: Blunt-end cloning

Blunt-end cloning is one of the easiest and most versatile methods for cloning dsDNA into plasmid vectors. It is easy because the blunt-ended insert requires little to no preparation. Read an overview of blunt-end cloning with tips for making this cloning approach successful.

Fancy a cup of milk? Baby spiders suckle ‘spider milk’ from their mothers

Mammals provide their offspring with milk during early development, yet this behaviour is rare in other parts of the animal kingdom. Now, a research team has found that young jumping spiders (Toxeus magnus) lap up nutritious milk droplets secreted from the mother’s underside for nearly 40 days before they leave the nest.

Scientists explain how wombats drop cubed poop

Wombats, the chubby and beloved, short-legged marsupials native to Australia, are central to a biological mystery in the animal kingdom: How do they produce cube-shaped poop? Patricia Yang, a postdoctoral fellow in mechanical engineering at the Georgia Institute of Technology, set out to investigate.

New supplier: Membrane Solutions

We are excited to introduce our latest supplier - Membrane Solutions, a premier manufacturer of sterile filtration solutions. It's product range includes sterile syringe filters and bottletop filters with 0.22 um and 0.45 um filters.

Tethered antibodies offer broad Flu protection in mice

Tethering four antibodies together may offer protection against all types of influenza virus known to infect humans, according to a study published recently in Science. The research was done as part of an international collaboration including Scripps Research Scientists.

A novel, high-fidelity Cas9 improves CRISPR editing accuracy without sacrificing performance

The introduction of the CRISPR-Cas9 system for genome editing has been an incredible boon for biological research. As our understanding of CRISPR technology increases, so does our awareness of the off-target editing events carried out by Cas9 nuclease. Existing CRISPR guide RNA design tools, such as CRISPR Design (MIT [1]) and CCTop (CRISPR-Cas9 Target online predictor, Heidelberg University [2]), attempt to predict off-target editing of the guide RNAs. However, these tools are limited by an incomplete understanding of the factors that cause Cas9 to cleave at incorrect sites.

Molecule from fungi might whack weeds

The enzyme dihydroxyacid dehydratase is a promising weed-control target, but synthetic molecules designed to block the enzyme have not worked when tested on plants. Now, researchers have successfully targeted the protein with a molecule from fungi, aspterric acid, and they say the molecule could become an effective weed killer with a new mode of action.

Staphylococcus Genome Set Reveals Bug's Host-Switching History

An international team led by investigators at the University of Edinburgh has shown that pathogenic Staphylococcus aureus strains likely gain the ability to bounce between host species by swapping host-specific mobile genetic elements and other sequences. Read more...

High-fidelity Cas9 provides highly efficient genome editing with reduced off-target effects in primary cells

Read how a novel, high-fidelity Cas9 enzyme potentiates the use of CRISPR technology in clinical applications. This high-fidelity Cas9 enzyme, now available as Alt-R HiFi Cas9 V3 Nuclease, achieves highly efficient and specific genome editing in hard-to-edit primary cells.

Read our July newsletter

New Lubio website, NASA's Astro-mice, antibodies from Biorbyt & more

New supplier: Norgen Biotek

Norgen has developed over 150 sample preparation kits for RNA, DNA, and protein purification for research purposes.

Meet our new supplier: Biorbyt

We are proud to add the antibody manufacturer Biorbyt to our portfolio. Based in Cambridge, one of Europe’s largest bioscience hubs, Biorbyt has a simple yet challenging mission: to provide the best service to the global scientific community.

New supplier: Larodan Lipids

Founded in 1963 and based at the Karolinska Institute, Sweden, Larodan develops and manufactures a comprehensive range of high quality, research grade lipids, manufactured by both extraction and purification from natural sources as well as by chemical synthesis.

Integrated DNA Technologies appoints LubioScience as distributor in Switzerland

SKOKIE, IL (May 2, 2017) – Integrated DNA Technologies (IDT), has signed a distributor agreement with LubioScience GmbH (LubioScience), based in Lucerne, Switzerland. Through LubioScience, researchers in Switzerland will benefit from local access to IDT’s full range of high quality reagents for genomics research, including custom oligonucleotides, and products for next generation sequencing, CRISPR genome editing, qPCR, and RNA interference.