Benzonuclease is a non-specific nuclease from Serratia marcescens that degrades both single- and double-stranded nucleic acids, including DNA and RNA, but exhibits no proteolytic activity. Its activity is identical with commercially available Benzonase. It is ideal for the removal of nucleic acid contaminants from protein samples and applications where complete digestion of nucleic acids is desirable, such as bioprocessing applications or reduction of viscosity in samples caused by genomic DNA.
Our recombinant Benzonuclease is expressed in yeast and purified to > 95% purity.
Ideal for:
- Removal of nucleic acids (DNA & RNA) from protein lysates
- Reduction of viscosity in protein lysates
Key advantages:
- Recombinant, engineered nuclease from Serratia marcescens
- Purified to > 95% purity for molecular biology applications
- Guaranteed free of nucleic acids and proteases
- Significantly cheaper than Benzonase from the market leader
Performs as well as the industry standard
Benzonuclease from Lubio is exactly as effective in removing nucleic acid from protein lysates as the significantly more expensive Benzonase from Competitor M.
1 ug of herring sperm DNA was digested for 30 minutes at 37°C with the indicated amounts of nuclease from either Lubio or Competitior M. Lane C: control, no nuclease. Lanes 1-5: 2.5u, 1.25u, 0.625u, 0.312u and 0.156u nuclease. Lane 6: 1 kb DNA ladder
Product literature
| Filename | Download |
|---|---|
| Benzonuclease for purification applications |  |
Product details
| Cat-No. | Item | Size | Price (CHF) |
|---|---|---|---|
| RE1001-25KU | Benzonuclease, recombinantly expressed and purified, for molecular biology applications | 25000 units | 219.00 |
On stock in Switzerland. Also available in bulk quantities, please inquire.
Benzonase is a trademark of Merck.