Webinar: Friendly CRISPR Clash

Friendly CRISPR Clash: First Back2Back Academic and Industrial CRISPR Webinar in Switzerland

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Online

Dissecting the molecular mechanism of Cas9 specificity

Academic Presentation (30 Minutes):

Speaker: Dr. Martin Pačesa, Group of Prof. Bruno Correia, EPFL - Laboratory of Protein Design and Immunoengineering

Abstract:

CRISPR-Cas9 has been widely employed for a variety of genome engineering applications. However, Cas9 can bind and cleave partially complementary off-target sequences, which raises safety concerns for its use in clinical applications. In this webinar, we will discuss the recent structural investigations that shed light on the molecular mechanisms underlying Cas9 specificity and off-target discrimination. We also highlight how these experimental results can help to develop a more efficient and specific CRISPR-Cas9 gene editing system.

 

Improved methods for CRISPR HDRresearch using Alt-R™ modified donors and Alt-R HDR Enhancer V2

Industrial Presentation (30 Minutes):

Speaker: Jennifer Stott, Commercial and Technical Specialist CRISPR & Functional Genomics - IDT

 

 

When: Wednesday, 29. June 2022 at 16:00 CEST 

Where: Online (free)

 

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