Webinar: An improved solution for generating large CRISPR HDR knock-ins
Introducing Alt-R™ HDR Donor Blocks and Alt-R™ HDR Enhancer V2
Online
CRISPR-based homology-directed repair (HDR) is an invaluable tool to facilitate specific mutations in a genomic region of interest in research studies. While many methods have been reported for improving HDR efficiency, achieving precise changes via HDR remains a challenge, particularly for large knock-ins. These insertions can be generated via HDR using enzymatically-generated donor templates. In this webinar you will learn:
Topics covered:
- How dsDNA donor templates with novel end-modifications improve the frequency of HDR and reduce homology-independent (blunt) insertion events.
- How the addition of Alt-R HDR Enhancer V2, a small molecule compound, can further improve HDR rates.
- Design considerations when using large dsDNA templates for successful HDR experiments.The composition and capabilities of exosomes.
Speaker: Jessica Woodley, MS - IDT Research Scientist Molecular Genetics Research Group
Moderator: Mollie Schubert, MS - IDT Research Scientist Molecular Genetics Research Group
When: Tuesday 22. March 2022 at 16:00 CET
Where: Online (free)
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