MedChemExpress (MCE) is a leading global brand in the life science industry, providing high-quality bioactive molecules and cutting-edge solutions for scientific research. MCE is committed to promoting the progress of human scientific research and pharmaceutical development, making R&D and production more efficient.
MedChem Express provides a wide range of research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and Natural compounds for laboratory and scientific use. MedChemExpress pays great attention to the purity, stability and activity of all its compounds.
MedChemExpress Portfolio
- Small molecules
- Active Pharmaceutical Ingredients (APIs)
- Natural compounds
- Inhibitor libraries
- Reference compounds
Quality Assurance
MedChemExpress (MCE) pays strict attention to quality control. Not only does MCE provide the chemical test data, such as HNMR, LC-MS and HPLC, but they also provide the information of stability and activity of the products.
- Stringent quality control and verification system, certified by ISO 9001, CNAS quality management system.
- Provide a range of quality inspection reports, including HNMR, LC/MS, HPLC, chiral analysis, elemental analysis, SDS-PAGE, SEC-HPLC, MS, FACS, affinity detection, activity detection, etc.
The chemists at MedChemExpress are highly experienced in preparing biologically active molecules that are both structurally and synthetically diverse. The volume of their product ranges from milligrams to kilograms scale. With rich experiences in customized chemical synthesis, MCE ensures on-time delivery of diversified compounds to meet all clients’ different requirements.
MedChemExpress has been named CiteAb Biochemicals supplier to watch in 2021.
Compound screening libraries
Ready-to-use MedChemExpress compound libraries consist of over 7,000 small molecules with validated biological and pharmacological activities. They are available for high-throughput screening (HTS) and high-content screening (HCS). Compound libraries are useful professional tools for drug discovery and new indication research.
- Safety and effectiveness have been confirmed by literature, patent reports and clinical research. Many products are FDA-approved.
- Focus on hundreds of targets that are key components in the fields of GPCR, kinase, anti-cancer, epigenetics, stem cell biology, etc.
- Detailed biological and chemical information is provided for every compound together with the LC/MS and NMR reports.
MedChemExpress offers over 300 exclusive compounds worldwide and tracks the latest scientific innovations to give customers access to the newest small molecules.
Cell Counting Kit-8
MedChemExpress Cell Counting Kit-8 (CCK-8) allows sensitive colorimetric assays for the determination of cell viability in cell proliferation and cytotoxicity assays.
The kit provides a tool for studying induction and inhibition of cell proliferation in any in vitro model. Cell Counting Kit-8 (CCK-8) allows very convenient assays by utilizing highly water-soluble tetrazolium salt.
CCK-8 by MedChemExpress is a one-bottle solution, ready to use. CCK-8, being nonradioactive, allows sensitive colorimetric assays for the determination of the number of viable cells in cell proliferation and cytotoxicity assays.
1. More sensitive than MTT, MTS, or WST-1
2. No toxicity to cells
3. Simple steps (no thawing necessary)
4. Stable one bottle solution : 1 year at 4°C
Inhibitory Antibodies
MedChemExpress Inhibitory Antibodies are monoclonal antibodies (mAbs) that have been extensively used in the hottest research areas, such as cancer, immunology and infection. These monoclonal antibodies (mAbs) bind monospecifically to certain cells or proteins, thus stimulating the immune system to attack the malignant tumor cells and preventing tumor growth by blocking specific cell receptors. They can inhibit PD-1, PD-L1, EGFR, VEGFR, TNF-alpha or other targets which are unusually active in diseases, such as non-Hodgkin lymphoma, Hemophilia A, renal cell carcinoma, Parkinson's disease and metastatic HER2-positive breast cancer. For example, by binding to VEGF, the humanized monoclonal antibody prevents VEGF from interacting with its receptors, thereby inhibiting new vessel growth. Lambrolizumab targets the programmed cell death 1 (PD-1) receptor of lymphocytes. By preventing the binding of its ligands (PD-L1 and PD-L2), Lambrolizumab induces an antitumor immune response.
MedChemExpress Bestsellers
| Product / CAS | Size | Product No. |
|---|---|---|
| Cell Counting Kit-8 | 100T, 500T, 3000T, 12'000T | HY-K0301 |
| MG-132 | 10mg, 25mg, 50mg, 100mg, 200mg, 500mg | HY-13259 |
| Rapamycin | 1ml, 10mg, 25mg, 50 mg, 100mg, 500mg, 1g, 2g, 5g | HY-10219 |
| Protease Inhibitor Cocktail | 1ml, 10 x 1ml, 50 x 1ml, 100 x 1ml | HY-K0010 |
| CAS. Nr. 25316-40-9 | 1ml, 50 mg, 100mg, 200mg, 500mg, 1g | HY-15142 |
| CAS. Nr. 54-05-7 | 1ml, 100mg, 200mg, 500mg, | HY-17589A |
| CAS. Nr. 763113-22-0 | 1ml, 10mg, 50 mg, 100mg, 500mg, 1g, 2g | HY-10162 |
| CAS. Nr. 85622-93-1 | 1ml, 10mg, 50 mg, 100mg, 200mg, 500mg, 1g | HY-17364 |
| CAS. Nr. 205923-56-4 | 1mg, 5mg, 25mg, 50 mg | HY-P9905 |
| Bucladesine sodium | 1ml, 50 mg, 100mg | HY-B0764 |
For research use only. We do not sell to patients.
Documentation
| Filename | Download |
|---|---|
| MCE - Topselling products |  |
| MCE_Compound-Screening-Libraries_web_23.pdf | |
| MCE - Inhibitors, agonists and compound library products | |
| MCE - Cancer research products | |
| MCE - Immunology research products | |
| MCE - Neuroscience research products | |
| MCE - CRO-CDMO services | |
