With a 20-year history of quality results, GeneTex sets itself apart from other antibody companies by taking the necessary steps to properly validate their antibodies. Antibody validation remains an industry-wide challenge with ramifications that can impact progress in the life sciences and medicine.
We strive to serve and accelerate life science research by creating essential biomedical reagents where quality can be found in every vial.
Assuring antibody quality
At GeneTex, stringent validation protocols have been established to test their antibodies for various applications, including WB, IP, IHC, IFA, FACS, and ELISA, using cell lines with known target protein expression levels and a diverse array of tissue samples. Quality consistency between lots is maintained through a combination of pre-qualified individual lots, dominant clones, and thorough quality control.
The five pillar antibody validation method
In order to optimize performance, quality and specifity of their antibodies, GeneTex employs various analytic validation strategies in their five pillar method (pdf with five pillar details).
Top products
HIF1 alpha antibody (GTX127309)
GeneTex is proud to introduce its well-cited HIF1α rabbit polyclonal antibody that demonstrates superior sensitivity and specificity for a broad array of applications and species. This reagent has been thoroughly validated through shRNA knockdown, CoCl2 and hypoxia induction, and overexpression. It remains in a market-leading position with over 80 citations and multiple positive customer reviews listed on the datasheet.
PARP antibody (GTX112864)
GeneTex’s “PARP antibody [N2C1], Internal” bears the distinction of having had its performance and specificity confirmed by testing that embraces all five of our “Pillars of Antibody Validation”. In addition, it has been cited in multiple publications for its utility in studying DNA repair, genomic stability, and programmed cell death across different species.
beta Amyloid (1-42) antibody (GTX134510)
GeneTex’s “beta-Amyloid (1-42) antibody – Conformation-Specific” can specifically detect amyloid plaques in the Alzheimer's disease brain by IHC-P analysis. The superior specificity and sensitivity of this antibody were confirmed by dot blot, ELISA and side-by-side IHC-P comparison with a competitor's product.
PD-L1 antibody (GTX104763)
GeneTex proudly offers an outstanding PD-L1 antibody (GTX104763) that can be used for WB, ICC/IF, IHC-P, and IHC-Fr. The quality of this antibody was demonstrated through stringent validation that included knockdown, interferon-gamma induction, and cross-reactivity testing.
HistoMAX - optimized antibodies for immunohistochemistry
Immunohistochemistry (IHC) is an indispensable application routinely employed in academic and clinical research as well as in patient care. In addition to the quality of tissue section preparation, the pivotal component determining the reliability of IHC data is the suitability of the antibody used. This can only be assessed through strict and focused reagent validation for this assay.
With this in mind, GeneTex is proud to introduce its HistoMAX product line that consists of antibodies specifically vetted for IHC. All of these reagents were extensively evaluated for IHC utilizing formalin-fixed normal and cancer tissue microarrays to guarantee specificity and best-in-class performance. Only antibodies that have passed these stringent performance criteria for IHC will be added to the HistoMAX portfolio.
Featured HistoMAX antibodies
Download HistoMAX flyers
| Filename | Download |
|---|---|
| GeneTex HistoMAX flyer |  |
| genetex_genetex_IHC-ValidatedRecombinantAntibodies_A4-DM-300dpi-rgb_23083118_719.pdf | |
Primary Antibodies
Various analytic validation strategies ensuring both consistent quality and specificity. In line with guidelines described by the International Working Group on Antibody Validation (IWGAV).
Validation methods and citation support indicated.
Antibody panels available.
Polyclonal, monoclonal and recombinant antibodies.
Recombinant antibodies
Recombinant antibodies have several advantages over traditional antibodies, including improved specificity and reduced immunogenicity. They are widely used in research, diagnostics, and therapeutics.
Discover Recombinant antibodies from GeneTex.
Validated Antibodies
Validated antibodies are antibodies that have been rigorously tested to ensure their specificity, sensitivity, and reproducibility for a particular application. This involves using appropriate controls and experimental conditions to confirm that the antibody recognizes its intended target with minimal cross-reactivity with other proteins. Validation is critical to ensure that the results obtained using the antibody are reliable and meaningful.
Secondary Antibodies
>1000 secondary antibodies with different conjugates for full flexibility in experimental design.
Specialized EasyBlot® secondary antibodies for the specific recognition of non-denatured primary antibodies used for western blot assays that commonly follow IP/co-IP protocols.
Reactivity: rabbit, mouse, hamster, rat, goat, sheep, chicken
Other antibody products
- Antibody panels (high-quality and highly cited antibodies in small amounts)
- ELISA kits and antibody pairs
- Isotype controls
- Custom antibodies
Other products
- Recombinant proteins and peptides COVID-19
- FFPE slides from cell lines, organs etc.
- Lysates
- Serums and plasmas from various animals
- Reagents and research kits
Documentation
| Filename | Download |
|---|---|
| GeneTex - SARS-CoV-2/Covid-19 product brochure | |
| GeneTex - Antibodies for virology research brochure | |
| Genetex - Cancer research antibodies pamphlet | |
| Genetex - EGFR signaling antibodies flyer | |
| Genetex - Cell cycle antibodies flyer | |
| Genetex - Neuroscience research antibodies pamphlet | |
| Genetex - Ion channel antibodies pamphlet | |
| Custom antibody service by GeneTex (flyer) | |
